When you think of pneumonia, you probably picture a cold that turned bad or the flu that stuck around too long. But fungal pneumonia, a lung infection caused by fungi, not viruses or bacteria. It's rare in healthy people, but can be life-threatening if you're immunocompromised. Unlike the flu, it doesn’t spread from person to person. Instead, you breathe in spores from the environment—dirt, bird droppings, decaying wood—and those spores settle in your lungs.
Three main fungi cause most cases: Histoplasma, a mold found in soil enriched with bird or bat droppings, common in the Ohio and Mississippi River valleys; Coccidioides, often called Valley Fever, native to dry desert regions like Arizona and California; and Aspergillus, a mold that lives everywhere, from compost piles to air conditioning units. Each one behaves differently. Histoplasmosis might feel like a mild flu. Coccidioidomycosis can cause joint pain and rashes along with coughing. Aspergillosis often attacks people with asthma or prior lung damage.
Most healthy people breathe in these fungi every day and never get sick. But if you’re on chemotherapy, have HIV, take long-term steroids, or had an organ transplant, your body can’t fight back. That’s when fungal pneumonia turns dangerous. It’s often misdiagnosed because symptoms—cough, fever, shortness of breath, chest pain—look just like bacterial pneumonia. Blood tests, chest X-rays, and sputum cultures are needed to spot the real cause.
Antibiotics won’t touch it. You need antifungal drugs—like itraconazole, voriconazole, or amphotericin B—and treatment can last months. In severe cases, surgery might be needed to remove infected tissue. Prevention? Avoid dusty areas in high-risk zones. Wear masks if you’re cleaning chicken coops, digging in soil, or exploring caves. If you’re immunocompromised, talk to your doctor about whether you should avoid certain environments altogether.
What you’ll find below are real, practical guides that connect directly to this issue. You’ll read about how drug interactions affect antifungal treatments, how to track side effects of long-term antifungals, and how to recognize when a lingering cough is more than just a cold. These aren’t theoretical articles—they’re based on patient experiences, clinical data, and real-world pharmacy insights. Whether you’re managing a diagnosis, caring for someone who is, or just trying to understand why your doctor ordered a fungal test, this collection gives you the clarity you need.